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These enzymes are strongly FAD-dependent, and mutations often destabilize FAD-binding motifs or enzyme complexes, impairing fatty acid -oxidation and energy homeostasis

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Skin Research and Technology , 16(3), 348-354

[DOI] [PMC free article] [PubMed] [Google Scholar] 337.Dehghan M., Mente A., Zhang X., Swaminathan S., Li W., Mohan V., Iqbal R., Kumar R., Wentzel-Viljoen E., Rosengren A., et al